Título: A randomised trial of lung sealant versus medical therapy for
advanced emphysema

Autor: Carolyn E. Come, Mordechai R. Kramer, Mark T. Dransfield, Muhanned Abu-Hijleh, David Berkowitz, Michela Bezzi, Surya P. Bhatt, Michael B. Boyd, Enrique Cases, Alexander C. Chen, Christopher B. Cooper, Javier Flandes, Thomas Gildea, Mark Gotfried, D. Kyle Hogarth, Kumaran Kolandaivelu, William Leeds, Timothy Liesching, Nathaniel Marchetti, Charles Marquette, Richard A. Mularski, Victor M. Pinto-Plata, Michael A. Pritchett, Samaan Rafeq, Edmundo R. Rubio, Dirk-Jan Slebos, Grigoris Stratakos, Alexander Sy, Larry W. Tsai, Momen Wahidi, John Walsh, J. Michael Wells, Patrick E. Whitten, Roger Yusen, Javier J. Zulueta, Gerard J. Criner, and George R. Washko

Publicación: Eur Respir J

Fecha de publicación: 2015

Resumen: Uncontrolled pilot studies demonstrated promising results of endoscopic lung volume reduction using emphysematous lung sealant (ELS) in patients with advanced, upper lobe predominant emphysema. We aimed to evaluate the safety and efficacy of ELS in a randomised controlled setting.